| Andrew Duncan :
Synthetic Organic and Organometallic Chemistry; Catalysis ...........Assistant Professor |
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Development of chiral organic catalysts derived from 2-amino sugars: simple compounds for tricky tasks. |
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Ring-closing metathesis reactions of allenes: developing new methods for making synthetically challenging large-ring molecules.
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David Goodney:
Analytical and Environmental Chemistry.....................................................Associate Dean |
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Instrumental methods for
environmental analysis. For example, UV-visible spectroscopy
for measurement of pH. |
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Metal ions in the environment, particularly
interactions with living organisms and phytoremediation. |
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Analysis of antioxidants
in wine. |
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| Karen Holman: Inorganic, Bioinorganic, and Organometallic Chemistry...................Associate Professor |
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Ligand exchange reactions of Ru(II) and Ru(III) anti-cancer drugs using infrared spectroelectrochemistry. |
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X-ray spectroscopic determination of electron distribution in Ru-Cl bonds in ruthenium-based anti-cancer drugs and their derivatives. |
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Kinetics of short-lived intermediates generated by laser flash photolysis of metal nitrosyl and carbonyl complexes (in collaboration with Prof. Williamson). |
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Binding and cleavage studies of metal complexes with tRNA (in collaboration with Prof. Kirk). |
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| Tony Hoobler: Organic Chemistry..........................................................................Visiting Assistant Professor |
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The effect of steric, through-bond and through-space chlorine-chlorine interactions on the conformational stability of molecules and stereochemical outcomes of reactions. |
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The factors that influence the formation, structure and fate of the oxaphosphetane intermediate in the Wittig reaction. |
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The role of chlorine-substituted dienophiles and dienes on the stereochemistry of the Diels-Alder adduct. |
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The application of Spartan, a molecular mechanical and quantum chemical calculations program, to the theoretical study of reactions under kinetic and thermodynamic control. |
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| Sarah Kirk: Bioorganic Chemistry........................................................................................Assistant Professor |
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Design and synthesis of novel pharmaceuticals utilizing amino acid-aminoglycoside scaffolds. |
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Investigation of the binding betewen novel molecules and nucleic acid via fluorescence spectroscopy. |
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Define essential elements within novel molecules that dictate nucleic acid specificity. |
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| Art Payton: Theoretical Physical Chemistry.......................................................................Research Professor |
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Transport entropies and enthalpies of ions in solution. |
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Thermoelectric power: theory and experimental observations. |
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| Todd Silverstein: Biochemistry...............................................................................................................Professor |
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Toxicity of heavy metal ions and metal reactivity with enzymes. |
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Enzyme activity in non-aqueous deep eutectic solvents. |
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Photochemistry of sunscreens: does UV spectroscopy predict control of photoinduced free radical production? |
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How do lipid membrane surfaces differ from the bulk aqueous phase and from the membrane interior? Measuring pH variations. |
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Degradation of organic pollutants: using UV light and sonication to degrade PCB's, dioxins, antibiotics, and other pollutants. |
| Arwyn Smalley : Materials/Inorganic/Physical Chemistry..................................Visiting Assistant Professor |
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Analyze crystalline materials using powder X-ray diffraction, and use quantitative analysis to determine the amount of crystalline material present. |
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Use one (or more) of the principles of Green Chemistry to modify an existing Organic Chemistry laboratory experiment to make it greener. |
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Design a new physical chemistry laboratory experiment (or modify an existing one) to utilize differential scanning calorimetry (rather than bomb or solution calorimetry) to illustrate the concept of calorimetry in the class. |
| Chuck Williamson: Physical Chemistry..........................................................Chair and Associate Professor |
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Thermodynamics and spectroscopic properties of binary liquid mixtures. |
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Time-resolved spectroscopy and fast (nanosecond) kinetics. |
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Laser Doppler velocimetry. |
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